Verona Pharma PLC: Merck & Co. Poised for a $10 Billion Acquisition

In a significant move within the pharmaceutical sector, Merck & Co. is reportedly on the brink of finalizing a $10 billion acquisition of Verona Pharma PLC, a clinical-stage biopharmaceutical company based in London. This potential deal, highlighted by multiple financial news sources, underscores Merck’s strategic expansion into the respiratory disease market, particularly as it seeks to diversify its portfolio ahead of the patent expiration of its flagship cancer drug, Keytruda.

Strategic Expansion into Respiratory Therapeutics

Merck’s interest in Verona Pharma is driven by the latter’s specialization in developing therapeutics for respiratory diseases. Verona’s flagship product, Ohtuvayre, has already made a significant impact in the United States, where it is approved for the treatment of chronic obstructive pulmonary disease (COPD). Analysts are optimistic about Ohtuvayre’s potential, projecting its sales could peak at $4 billion by the mid-2030s. This acquisition would not only bolster Merck’s presence in the respiratory market but also provide a new revenue stream as Keytruda’s patent nears expiration.

Financial Terms and Market Reaction

The acquisition terms, as reported, involve Merck offering $107 per American Depository Share (ADS) for Verona, representing a 23% premium over Verona’s closing price on the preceding Tuesday. This valuation places Verona at approximately $10 billion, marking it as Merck’s largest acquisition in the past two years. The announcement has already had a noticeable impact on Verona’s stock, which has seen a significant uptick, reflecting investor confidence in the deal’s strategic value.

Verona’s Growth Trajectory

Verona Pharma has demonstrated robust growth, particularly with Ohtuvayre, which generated $71.3 million in revenue in the first quarter of 2025 alone. Analysts predict that Ohtuvayre’s annual sales could reach at least $1 billion, further enhancing Verona’s attractiveness as a target for acquisition. The company’s focus on respiratory diseases aligns well with Merck’s strategic objectives, making this acquisition a potentially transformative move for both entities.

Market Implications

This acquisition is poised to reshape the competitive landscape in the pharmaceutical industry, particularly in the respiratory therapeutics segment. For Merck, it represents a strategic pivot to mitigate the impact of Keytruda’s patent expiration and to capitalize on the growing demand for respiratory treatments. For Verona, the acquisition by a pharmaceutical giant like Merck offers an opportunity for accelerated growth and expanded market reach.

As the deal progresses towards finalization, stakeholders in both companies are closely watching the developments, anticipating the potential synergies and market advantages that could arise from this significant merger.