Financial Market Update: Profusa Inc. Faces Significant Decline

In the latest pre-market trading session on Tuesday, July 29, 2025, several stocks experienced notable movements. Among the stocks in the red, Profusa, Inc. (PFSA) saw a significant decline, dropping over 37% to $1.22. This movement places Profusa Inc. among the most affected stocks in the pre-market session, alongside AIM ImmunoTech Inc. (AIM) and Bakkt Holdings, Inc. (BKKT), which also experienced substantial declines.

Profusa Inc. Overview

Profusa Inc., a company listed on the Nasdaq, operates with a market capitalization of $23,380,000 USD. The company’s stock has been volatile over the past year, with a 52-week high of $5.50 on July 10, 2025, and a 52-week low of $0.651 on July 24, 2025. As of July 27, 2025, the close price was $1.94. The company’s price-to-earnings ratio stands at -0.462288, indicating a lack of profitability.

Market Context

The pre-market session also saw significant gains for several companies. DURECT Corporation (DRRX) led the gains with an increase of over 267% to $2.03, followed by Salarius Pharmaceuticals, Inc. (SLRX) up over 146% to $1.83, and ScanTech AI Systems Inc. (STAI) up over 49% to $1.00. Other notable movers included Sarepta Therapeutics, Inc. (SRPT) and GeneDx Holdings Corp. (WGS), which saw increases of over 37% and 28%, respectively.

Industry News

In other industry news, Hot Chili Limited reported significant findings from its phase-one Reverse Circulation drilling program at the La Verde porphyry discovery. The program confirmed a substantial copper-gold discovery, with mineralization extending over 1 km in length and up to 750 m in width from near the surface. The discovery remains open laterally and at depth, with over half of Hot Chili’s drill holes ending in mineralization. Significant intercepts included 389 m grading 0.4% Cu and 0.1 g/t Au from 4 m depth to end-of-hole (DKP030), and 286 m grading 0.3% Cu and 0.1 g/t Au from 4 m depth (DKP027).

Conclusion

Profusa Inc.’s significant decline in the pre-market session highlights the volatility and challenges faced by the company. Meanwhile, Hot Chili Limited’s promising drilling results at the La Verde porphyry discovery offer a positive outlook for the mining sector. Investors and market watchers will continue to monitor these developments closely.