Vaxart, Inc., a biotechnology company based in South San Francisco, USA, has been making strides in the health care sector with its innovative approach to flu vaccination. Specializing in the development and marketing of oral flu vaccines, Vaxart’s technology is designed to stimulate the immune system of the gut, thereby generating both systemic and mucosal immune responses. This unique method of vaccine delivery positions Vaxart as a leader in the biotechnology industry, particularly within the niche of oral immunization.

As of December 30, 2025, Vaxart’s stock closed at $0.35 on the Nasdaq stock exchange, reflecting a significant decline from its 52-week high of $0.98 on January 6, 2025. Despite this downturn, the stock has shown resilience, having risen from its 52-week low of $0.26 on July 8, 2025. Over the past year, Vaxart’s share price has experienced fluctuations of approximately 30%, indicative of the volatile nature of the biotechnology sector.

Recent financial reports highlight a challenging period for Vaxart, with the stock dipping below its two-hundred-day moving average as of December 25, 2025. This movement signals a short-term bearish trend, raising concerns among investors about the company’s immediate financial trajectory. The price-to-earnings ratio of -1.58 underscores these concerns, reflecting negative earnings per share. This metric suggests that Vaxart is currently operating at a loss, a common scenario for companies in the biotechnology sector that are heavily invested in research and development.

Despite these financial challenges, Vaxart maintains a price-to-book ratio of 3.0979, indicating that the market values the company at approximately three times its book value. This valuation premium suggests that investors hold a positive outlook on Vaxart’s long-term potential, likely due to its innovative vaccine technology and the growing demand for more convenient and effective flu prevention methods.

With a market capitalization of $84,230,000, Vaxart continues to serve a global customer base through its online platform, www.vaxart.com . The company’s commitment to advancing oral vaccine technology remains a key driver of its strategic initiatives, as it seeks to capitalize on the increasing interest in non-invasive vaccination methods.

In summary, while Vaxart faces short-term financial hurdles, its pioneering approach to flu vaccination and strong market valuation indicate a promising future. Investors and industry observers will be closely monitoring the company’s progress as it navigates the complexities of the biotechnology landscape and strives to achieve its long-term objectives.